Research (Scientific) Associate Director, Computational Chemistry Job at Takeda, Boston, MA

ZGRxT05vNzhhMW9seFhWNk13OG5nc0hlcVE9PQ==
  • Takeda
  • Boston, MA

Job Description

Job Description At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. Objective / Purpose: As a Computational Chemistry Leader, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Data Scientists, Structural Biologists, Pharmacologists, and Biologists to provide computational expertise to advance drug discovery projects. Contribute to drug discovery efforts across various modalities including small molecules, bifunctional degraders, peptides, RNA/oligonucleotides, and biologics. Implement and execute innovative computational methodologies and tools such as AI approaches to support drug discovery efforts. Accountabilities: Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment. Identify, develop, validate, and implement innovative computational approaches that improve research productivity and success. Provide crucial technical knowledge and input to project teams to drive decision-making in drug discovery projects. Build and develop a strong team of Computational Chemists to high productivity levels. Demonstrate leadership and enterprise thinking in managing a multi-disciplinary team.

DIMENSIONS AND ASPECTS:

Expertise in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, data mining, machine learning, cheminformatics, clustering, similarity & diversity analysis. Significant industry experience contributing as a Computational Chemist on drug discovery projects. Strong impact in progressing discovery projects from hits to clinical leads. Extensive knowledge & experience in using a variety of tools for hit ID. Provide project teams with computational strategies to inform, influence, and prioritize compound designs for potency/selectivity and improve ADME/Tox endpoints. Ability to effectively integrate emerging generative chemistry methods and other modern machine learning and artificial intelligence (AI) applications in small molecule drug discovery. Proficiency with state-of-the-art computational chemistry software. Network with renowned researchers in computational chemistry/AI.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

PhD degree in a relevant scientific discipline. 6+ years of industry (pharma/biotech) drug discovery experience required. For Location: Boston, MA U.S. Base Salary Range: 149,100.00 - 234,300.00 EEO Statement: Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt: Yes #J-18808-Ljbffr Takeda

Job Tags

Full time, Local area, Remote job, Worldwide,

Similar Jobs

Domino's Franchise

Pizza Maker Starting Up to $12/Hr (09703) 1139 W Main St Job at Domino's Franchise

 ...Job Description Job Description Company Description AMNJ Ent Inc is a Locally owned and family-operatedFranchise of Domino's Pizza. We are people-focused and care and support the community. We take pride in our team members and our team members take pride... 

Orioli Restaurant Group

General Manager - Fine Dining Restaurant General Manager Job at Orioli Restaurant Group

General manager Orioli Restaurant Group, the premier Italian restaurant group here in the 'famed' Woodlands Tx, is expanding its horizons of cuisines and service. Over the past 20 years the Orioli Family has chiseled out their company's foundation with the mantra of... 

PsychiaTreat MNGT, LLC.

Psychiatrist Job at PsychiaTreat MNGT, LLC.

 ...We are actively recruiting psychiatrists who embrace a hybrid model, combining both in-person and telehealth services, while enjoying flexible...  ...M.D./D.O. with Board Eligibility or Board Certification in Psychiatry. About PsychiaTreat Our mission is to provide... 

MD Anderson

Research Assistant I - Immunology Job at MD Anderson

 ...thermocycler and flow cytometer. 5. Some protocols require work on weekends/holidays and time away must be coordinated with other staff to...  ...disposal of dead animals, biohazards and used needles. 4. Assist in maintaining animal inventory by cross checking that the cage... 

NuWest Travel Nursing

Travel Nurse RN - PACU - Post Anesthesia Care - $2,319 per week Job at NuWest Travel Nursing

 ...NuWest Travel Nursing is seeking a travel nurse RN PACU - Post Anesthesia Care for a travel nursing job in Salem, Massachusetts. Job Description & Requirements ~ Specialty: PACU - Post Anesthesia Care ~ Discipline: RN ~ Start Date: 02/25/2025~ Duration: 1...